Basically what was happening was all mail from mailer-daemon@my.box.net and root@my.box.net was being rejected with:
sender verify defer for <root@my.box.net>: require_files: error for /root/.spamassassinenable: Permission denied
Turns out there were the exim checks for SA in the exim conf, sa_virtualuser directives, as we run mailscanner these are not used, yet seems to check them anyway, given the fact the config will be re-written on upgrade I figured it best to edit the config via WHM, however the lines in the config file didnt exist there (not even in the non-editable bit) so I needed to manually remove them to get things working again, however I am now concerned that they will re-appear when a newer exim RPM is available.
Any advice greatly welcomed!



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