I was unable to find the solution on this forum, so hopefully this can help someone else in a similar situation.

I am running CentOS and just updated to easyapache3. I had no problem with the installation of Apache2 it worked like a charm, except I clicked on the build button rather than the configure in the Update Apache area. I then attempted to upgrade to MySQL5 by switching in the Tweak Setting of WHM. Following the instructions I ran /scripts/mysqlup5. I was not watching the terminal screen and the install appeared to complete just fine. After later looking back I was getting the following error:

pmdb: PANIC: fatal region error detected; run recovery
error: db4 error(-30978) from dbenv->open: DB_RUNRECOVERY: Fatal error, run database recovery

I then attempted to run Apache Update over again and was receiving the error: Could not ensure pkglist 'mysql-devel, zlib-devel, flex, zlib'

When I attempted to run the database recovery rpm --rebuilddb I received the same error as when running /scripts/mysqlup. At http://www.rpm.org/hintskinks/repairdb/ I found out that I needed to delete my locking files rm -f /var/lib/rpm/__db* then I rebuilt the database with rpm -vv --rebuilddb. Then I went back to /scripts/mysqlup and it ran without errors. I then did an Update Apache and I now have Apache2 and MySQL 5 running.