Thanks yapluka
I tried to do it.
It worked fine for me.
php.ini is linked to Zend
PHP Code:
php.ini -> /usr/local/Zend/etc/php.ini
When I replaced Safe_mode = on to = off .. it converted the file and removed the link:
PHP Code:
replace "safe_mode = On" "safe_mode = Off" -- /usr/local/lib/php.ini ; /etc/init.d/httpd restart
/usr/local/lib/php.ini converted
/etc/init.d/httpd restart: httpd restarted
Also when I did it visa versa:
PHP Code:
replace "safe_mode = Off" "safe_mode = On" -- /usr/local/lib/php.ini ; /etc/init.d/httpd restart
/usr/local/lib/php.ini converted
/etc/init.d/httpd restart: httpd restarted
Then I lost Zend. All sites with zend scripts are down. Thanks GOD I had a backup of my php.ini file 
Any fix!