Block outgoing mail with From address that doesn't exist

Hello,

I would like to block outgoing email from users who authenticate with a valid username/password, but use a non-existent "From" address to send their emails.
I've read about the "Experimental: Rewrite From: header to match actual sender" option, but from what I can tell this will only show an informational message in the exim logs - it will not actually block the outgoing email.

Think of a mail client configured with proper credentials for the incoming/outgoing mailserver (ie. info@domain.com) but with a "From" address that does not exist (ie first.lastname@domain.com)
With the default configuration, the email will go through and will get delivered to the destination email address (the receiver will of course not be able to reply, since replying to first.lastname@domain.com will go nowhere).
Is there any option to block this email from even getting send? Can exim check that the From address does not exist on the server and block the email from getting sent?

Thanks in advance,
George