Hi
@Rajesh Chauhan
htaccess files can't be processed by nginx, so anything that will only be served through nginx won't support htaccess. However, Enginetron mainly works as a proxy in front of Apache to handle static files, this means it shouldn't break web applications from functioning.
If you're looking into caching solutions for your cPanel/WHM server, you might want to take a look into LiteSpeed Web Server Enterprise which is a drop-in replacement for Apache and understands htaccess files just fine. Additionally, the web server is officially supported by cPanel, where Enginetron isn't.