This depends on the intended use.
mod_php (DSO) > Fast, low memory consumption, low cpu consumption. It allows you to use accelerators such as opcache. Running inside the Apache chroot is unsafe.
Suphp > It is slow, low memory consumption but high cpu consumption, does not allow you to use accelerators such as opcache, but it is safe.
One question I see come up often for users setting up their own web servers involves how they run PHP. Nearly everyone I know who runs their own server has questions about this that usually fall in one of two areas. First, they have installed WordPress, Drupal, or another CMS and can’t get...
chriswiegman.com
I suggest you try mod_lsapi.
mod_lsapi is an Apache module based on the LiteSpeed Technologies API that provides significant improvements in speed and resource use for PHP websites.
blog.cpanel.com