Yes, aware of the potential WP plugin issues but less worried related to other stuff since PHP 7 has been out a long time and I use minimal plugins and they are pretty major (not obscure) ones.
So ya, that's why I asked as I figure by polling other users I can get a feel for how common the issues are (non Wordpress) and what they are.
Just to be safe, I'll probably spin up a separate server with separate Cpanel license, transfer the accounts in question, override the DNS by editng my LMHOSTS file temporarily to point the domains to the test server and test that way after doing a test upgrade. Still, would be nice to get an idea what I'm probably in for.